Key Terms To Know.
A measure of the amount of HIV in the body.
When ART is taken long enough to reduce the ability of the virus to make copies of itself in someone’s body.
Is the use of HIV medicines to treat HIV infection. Antiretroviral Therapy or ART is recommended for everyone who has HIV. ART helps people with HIV live longer, healthier lives and reduces the risk of HIV transmission.
When someone is on ART and the virus level in their body is so low that standard blood test cannot detect it.
HIV cannot be transmitted through sexual transmission when the viral load is below 200/ml
Backed By Research.
This trail found that immediate ART initiation reduced HIV transmission between serodiscordant couples by 93 percent.
From April 2005 to May 2015, the study enrolled 1,763 serodiscordant heterosexual couple from Botswana, Brazil, India, Kenya, Malawi, South Africa, Thailand, United States, and Zimbabwe. A total of 78 partners became infected with HIV during the study; of these, 46 were virologically linked to the HIV- positive partner, 26 were not linked, and six could be traced. Among the 46 linked cases, three were in the immediate treatment arm while 43 were in the delayed arm. Transmission occurred when viral suppression had not been achieved, either due to the timing of treatment (HIV was transmitted shortly before or after treatment initiation by the index partner) or treatment failure. Learn more
This study found no documented cases of sexual HIV transmission among serodiscordant couples when the index partner was virally surpressed.
From September 2010 to May 2014, the study enrolled 1,166 HIV serodiscordant couple (both heterosexual couples and men who have sex with men) from 14 European countries. All couples reported condomless sex, and the index partner was virally suppressed. A total of 11 HIV-negative partners became HIV infected during the study period, but none of the infections were phylogentically linked (i.e., newly infected partner did not acquire HIV from the enrolled index partner), making the within-couple transmission rate zero. Learn more.
PARTNER 2 Study4In
PARTNER 2, the PARTNER study continue from 2014 to 2018 with MSM serodiscordant couples only and found no linked HIV transmissions. Learn more.
This study from 2012 to 2015 found no instances of linked HIV transmission among 358 serodiscordant MSM couples from Australia, Thailand, and Brazil.
At baseline, 79.9 percent of the HIV – positive partners were on ART, and 77.9 percent were virally surpressed. About 57 percent reported anal sex with an outside partner during any point in the study follow-up period, and the study included a total of 16,889 acts of condomless anal sex. There were three new infections, but none of them were linked to the enrolled index partner. Learn more.